Cancer Specialists Hold Advanced Alternatives in Fight against Mesothelioma, though Prognosis Looks Grim
July 7th, 2009 by
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Doctors who specialize in cancer treatment determine what kind of treatment to administer to a patient. There are many options. There are no one size fits all treatment regimen for peritoneal mesothelioma cancer patients. This is due to the cancers high mortality rate, rareness, low treatment success rate, and small number of studies to provide meaningful statistics.
Mesothelioma patients have historically had a bleak outlook, but doctors have recently made progress. Traditional treatments for cancer are surgery (removing the tumor and surrounding tissue), chemotherapy (poisoning cancerous cells) and radiation (killing cancer cells with radiation) There are problems with all three. Patients with mesothelioma have not responded well to traditional radiation therapy. In hopes to lessen damage to healthy tissue, researches are studying ways to aim radiation right at the tumor.
Surgery removes the mesothelial tissue around the tumor. This surgery is extensive and it is not clear how much the patient benefits. Most chemotherapy medication that work on other cancers typically do not work on mesothelioma, and different combinations of chemotherapy drugs have been tried without a lot of success. Similar to radiation, focus in research is focusing on treating the physical location of the tumor with emphasis on the pleural cavity.
The high-mortality rate for mesothelioma patients means cutting-edge techniques for cancer are tried out. These techniques include a biologic therapy called the agent interleukin 2 and anti-angiogenesis drugs like thalidomide. A new drug that has shown results in improving survival is pemetrexed (brand name Alimta).
Oncologists consider the stage of mesothelioma, the location of the tumor, the patient’s age and state of health at the time. Two exotic ways of attacking mesothelioma are gene therapy and photodynamic therapy. Clinical trials using these techniques are being offered to some of those who have mesothelioma.
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